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REST Antikörper (AA 542-570)

REST Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB36730 unconjugated
Produktnummer ABIN1538486
  • Target Alle REST Antikörper anzeigen
    REST (RE1-Silencing Transcription Factor (REST))
    Bindungsspezifität
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 542-570
    Reaktivität
    • 41
    • 10
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 40
    • 1
    Kaninchen
    Klonalität
    • 40
    • 1
    Polyklonal
    Konjugat
    • 23
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser REST Antikörper ist unkonjugiert
    Applikation
    • 27
    • 18
    • 10
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This REST antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 542-570 amino acids from the Central region of human REST.
    Klon
    RB36730
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product REST Primärantikörper
  • Applikationshinweise
    WB: 1:2000. WB: 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    REST Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Haltbarkeit
    6 months
  • Target
    REST (RE1-Silencing Transcription Factor (REST))
    Andere Bezeichnung
    REST (REST Produkte)
    Hintergrund
    Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.
    Molekulargewicht
    121872
    Gen-ID
    5978
    NCBI Accession
    NP_001180437, NP_005603
    UniProt
    Q13127
    Pathways
    Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity
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