FANCA Antikörper (AA 667-694)

Produktnummer ABIN1538566

Produktdetails anti-FANCA Antikörper

Target: FANCA (Fanconi Anemia Group A Protein (FANCA))

Bindungsspezifität: AA 667-694

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FANCA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FANCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 667-694 amino acids from the Central region of human FANCA.

Klon: RB23899

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: FANCA Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu FANCA

Target: FANCA (Fanconi Anemia Group A Protein (FANCA))

Andere Bezeichnung: FANCA (FANCA Produkte)

Synonyme: FA antikoerper, FA-H antikoerper, FA1 antikoerper, FAA antikoerper, FACA antikoerper, FAH antikoerper, FANCH antikoerper, AW208693 antikoerper, Fanconi anemia complementation group A antikoerper, Fanconi anemia, complementation group A antikoerper, FANCA antikoerper, Fanca antikoerper

Hintergrund: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia.

Molekulargewicht: 162775

Gen-ID: 2175

NCBI Accession: NP_000126, NP_001018122

UniProt: O15360

Pathways: DNA Reparatur