RNF144B Antikörper (AA 90-118)
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- Target Alle RNF144B Antikörper anzeigen
- RNF144B (Ring Finger Protein 144B (RNF144B))
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Bindungsspezifität
- AA 90-118
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RNF144B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This RNF144B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-118 amino acids from the Central region of human RNF144B.
- Klon
- RB37984
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product RNF144B Primärantikörper
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- Applikationshinweise
- WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- RNF144B Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
- Haltbarkeit
- 6 months
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- Target
- RNF144B (Ring Finger Protein 144B (RNF144B))
- Andere Bezeichnung
- RNF144B (RNF144B Produkte)
- Synonyme
- IBRDC2 antikoerper, PIR2 antikoerper, bA528A10.3 antikoerper, p53RFP antikoerper, BC025007 antikoerper, E130105P19Rik antikoerper, Ibrdc2 antikoerper, Pir2 antikoerper, ring finger protein 144B antikoerper, RNF144B antikoerper, Rnf144b antikoerper
- Hintergrund
- E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a TP53/p53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death, But, it is not an anti-apoptotic protein per se.
- Molekulargewicht
- 33697
- Gen-ID
- 255488
- NCBI Accession
- NP_877434
- UniProt
- Q7Z419
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