Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This RBPJ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-29 amino acids from the N-terminal region of human RBPJ.
AOS3 antikoerper, CBF1 antikoerper, IGKJRB antikoerper, IGKJRB1 antikoerper, KBF2 antikoerper, RBP-J antikoerper, RBPJK antikoerper, RBPSUH antikoerper, SUH antikoerper, csl antikoerper, AI843960 antikoerper, Igkjrb antikoerper, Igkrsbp antikoerper, RBP-J kappa antikoerper, RBPjk antikoerper, Rbpsuh antikoerper, Su(H) antikoerper, XSu(H) antikoerper, xsu(h)1 antikoerper, Su(H)1 antikoerper, Su(h)A antikoerper, ik:tdsubc_1e8 antikoerper, rbpj antikoerper, rbpsuh antikoerper, xx:tdsubc_1e8 antikoerper, Su(H)2 antikoerper, su(h)B antikoerper, recombination signal binding protein for immunoglobulin kappa J region antikoerper, recombination signal binding protein for immunoglobulin kappa J region S homeolog antikoerper, recombination signal binding protein for immunoglobulin kappa J region a antikoerper, recombination signal binding protein for immunoglobulin kappa J region b antikoerper, RBPJ antikoerper, Rbpj antikoerper, rbpj.S antikoerper, rbpja antikoerper, rbpjb antikoerper
Hintergrund
Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence.