This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This RANBP17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-175 amino acids from the N-terminal region of human RANBP17.
RGD1562576 antikoerper, RANBP17 antikoerper, 4932704E15Rik antikoerper, RAN binding protein 17 antikoerper, Ranbp17 antikoerper, RANBP17 antikoerper, ranbp17 antikoerper
Hintergrund
The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex, see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.