Cullin 2 Antikörper (N-Term)
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- Target Alle Cullin 2 (CUL2) Antikörper anzeigen
- Cullin 2 (CUL2)
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Bindungsspezifität
- AA 150-179, N-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Cullin 2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This CUL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-179 amino acids from the N-terminal region of human CUL2.
- Klon
- RB33843
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product CUL2 Primärantikörper
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anti-Cullin 2 (CUL2) (C-Term) antibody
CUL2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 2 (CUL2) (AA 18-182) antibodyCUL2 Reaktivität: Human, Maus, Ratte, Hund WB, IHC, IF, IP Wirt: Maus Monoclonal 4-CUL unconjugated
anti-Cullin 2 (CUL2) (C-Term) antibodyCUL2 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 2 (CUL2) (AA 591-742) antibodyCUL2 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 2 (CUL2) (C-Term) antibodyCUL2 Reaktivität: Human, Maus WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 2 (CUL2) (AA 1-100) antibodyCUL2 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Cullin 2 (CUL2) antibodyCUL2 Reaktivität: Human, Maus IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 2 (CUL2) (AA 1-100) antibodyCUL2 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 4G11 unconjugated
anti-Cullin 2 (CUL2) (AA 40-310) antibodyCUL2 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin 2 (CUL2) (C-Term) antibodyVerified CUL2 Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Ziege Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:1000. WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- CUL2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
- Haltbarkeit
- 6 months
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- Target
- Cullin 2 (CUL2)
- Andere Bezeichnung
- CUL2 (CUL2 Produkte)
- Hintergrund
- Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. May serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the ECS complex depends on the substrate recognition component. ECS(VHL) mediates the ubiquitination of hypoxia-inducible factor (HIF).
- Molekulargewicht
- 86983
- Gen-ID
- 8453
- NCBI Accession
- NP_001185706, NP_001185707, NP_001185708, NP_003582
- UniProt
- Q13617
- Pathways
- M Phase, Asymmetric Protein Localization, SARS-CoV-2 Protein Interaktom
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