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TMPRSS12 Antikörper (N-Term)

TMPRSS12 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB35931 unconjugated
Produktnummer ABIN1539224
  • Target Alle TMPRSS12 Produkte
    TMPRSS12 (Transmembrane (C-terminal) Protease, serine 12 (TMPRSS12))
    Bindungsspezifität
    • 7
    • 7
    • 7
    • 1
    • 1
    AA 26-54, N-Term
    Reaktivität
    • 16
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 16
    Kaninchen
    Klonalität
    • 16
    Polyklonal
    Konjugat
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser TMPRSS12 Antikörper ist unkonjugiert
    Applikation
    • 16
    • 12
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This TMPRSS12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-54 amino acids from the N-terminal region of human TMPRSS12.
    Klon
    RB35931
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    TMPRSS12 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Haltbarkeit
    6 months
  • Target
    TMPRSS12 (Transmembrane (C-terminal) Protease, serine 12 (TMPRSS12))
    Andere Bezeichnung
    TMPRSS12 (TMPRSS12 Produkte)
    Synonyme
    4930478A21Rik antikoerper, transmembrane protease, serine 12 antikoerper, transmembrane (C-terminal) protease, serine 12 antikoerper, TMPRSS12 antikoerper, tmprss12 antikoerper, Tmprss12 antikoerper
    Hintergrund
    TMPRSS12 (transmembrane protease serine 12) is a 348 amino acid single-pass membrane protein that belong to the peptidase S1 family and contains one peptidase S1 domain. The gene that encodes TMPRSS12 consists of nearly 45,000 bases and maps to human chromosome 12q13.12. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster, which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster, encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms which vary in severity depending on the extent of mosaicism.
    Molekulargewicht
    38605
    Gen-ID
    283471
    NCBI Accession
    NP_872365
    UniProt
    Q86WS5
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