ITM2C Antikörper (N-Term)

Produktnummer ABIN1539240

Produktdetails anti-ITM2C Antikörper

Target: ITM2C (Integral Membrane Protein 2C (ITM2C))

Bindungsspezifität: AA 27-55, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITM2C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: Pr

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ITM2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 amino acids from the N-terminal region of human ITM2C.

Klon: RB36714

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: ITM2C Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu ITM2C

Target: ITM2C (Integral Membrane Protein 2C (ITM2C))

Andere Bezeichnung: ITM2C (ITM2C Produkte)

Synonyme: 3110038L02Rik antikoerper, BRI3 antikoerper, Bricd2c antikoerper, E25 antikoerper, E25C antikoerper, ITM3 antikoerper, BRICD2C antikoerper, fj35c02 antikoerper, itm2c antikoerper, wu:fj35c02 antikoerper, zgc:66349 antikoerper, wu:fj52a04 antikoerper, zgc:92783 antikoerper, integral membrane protein 2C antikoerper, integral membrane protein 2Cb antikoerper, integral membrane protein 2Ca antikoerper, Itm2c antikoerper, ITM2C antikoerper, itm2cb antikoerper, itm2ca antikoerper

Hintergrund: Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity).

Molekulargewicht: 30224

Gen-ID: 81618

NCBI Accession: NP_001012532, NP_001012534, NP_112188

UniProt: Q9NQX7