TOPBP1 Antikörper (pSer1159)
(1 reference)-
- Target Alle TOPBP1 Antikörper anzeigen
- TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))
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Bindungsspezifität
- pSer1159
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TOPBP1 Antikörper ist unkonjugiert
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Applikation
- Dot Blot (DB)
- Homologie
- M
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This TOPBP1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1159 of human TOPBP1.
- Klon
- RB36342
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product TOPBP1 Primärantikörper
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anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) (AA 1253-1522) antibody
TOPBP1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) antibodyTOPBP1 Reaktivität: Human, Maus WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) (AA 1327-1435) antibodyTOPBP1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 6D12 unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) (AA 1-100) antibodyTOPBP1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) (AA 1-250) antibodyTOPBP1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) (AA 1-246) antibodyTOPBP1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) (AA 1253-1522) antibodyTOPBP1 Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) antibodyTOPBP1 Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) (AA 204-416) antibodyTOPBP1 Reaktivität: Human WB, IF Wirt: Maus Monoclonal 33-TopBP1 unconjugated
anti-Topoisomerase (DNA) II Binding Protein 1 (TOPBP1) (pSer1138) antibodyTOPBP1 Reaktivität: Human DB Wirt: Kaninchen Polyclonal RB36322 unconjugated
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- Applikationshinweise
- DB: 1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Phospho-TOPBP1-S1159 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the Phospho-TOPBP1-S1159 Antibody at -20 °C.
- Haltbarkeit
- 6 months
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-
: "Akt switches TopBP1 function from checkpoint activation to transcriptional regulation through phosphoserine binding-mediated oligomerization." in: Molecular and cellular biology, Vol. 33, Issue 23, pp. 4685-700, (2013) (PubMed).
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: "Akt switches TopBP1 function from checkpoint activation to transcriptional regulation through phosphoserine binding-mediated oligomerization." in: Molecular and cellular biology, Vol. 33, Issue 23, pp. 4685-700, (2013) (PubMed).
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- Target
- TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))
- Andere Bezeichnung
- TOPBP1 (TOPBP1 Produkte)
- Hintergrund
- This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands.
- Molekulargewicht
- 170679
- Gen-ID
- 11073
- NCBI Accession
- NP_008958
- UniProt
- Q92547
- Pathways
- Chromatin Binding
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