TOPBP1 Antikörper (pSer1159)

Produktnummer ABIN1539690

Produktdetails anti-TOPBP1 Antikörper

Target: TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))

Bindungsspezifität: pSer1159

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TOPBP1 Antikörper ist unkonjugiert

Applikation: Dot Blot (DB)

Homologie: M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TOPBP1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1159 of human TOPBP1.

Klon: RB36342

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: DB: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Phospho-TOPBP1-S1159 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the Phospho-TOPBP1-S1159 Antibody at -20 °C.

Haltbarkeit: 6 months

Referenzen für anti-TOPBP1 Antikörper (ABIN1539690)

Liu, Graves, Scott, Li, Lin: "Akt switches TopBP1 function from checkpoint activation to transcriptional regulation through phosphoserine binding-mediated oligomerization." in: Molecular and cellular biology, Vol. 33, Issue 23, pp. 4685-700, (2013) (PubMed).

Details zu TOPBP1

Target: TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))

Andere Bezeichnung: TOPBP1 (TOPBP1 Produkte)

Synonyme: RGD1562949 antikoerper, TOPBP1 antikoerper, cut5 antikoerper, F2P24.3 antikoerper, F2P24_3 antikoerper, meiosis defective 1 antikoerper, TOP2BP1 antikoerper, 1110031N14Rik antikoerper, 2810429C13Rik antikoerper, AI256758 antikoerper, D430026L04Rik antikoerper, mKIAA0259 antikoerper, TopBP1-A antikoerper, TopBP1-B antikoerper, Xmus101 antikoerper, XtopBP antikoerper, mus101 antikoerper, top2bp1 antikoerper, DNA topoisomerase II binding protein 1 antikoerper, topoisomerase (DNA) II binding protein 1 antikoerper, dna topoisomerase ii binding protein 1 (IC) antikoerper, transcription coactivator antikoerper, DNA topoisomerase II binding protein 1 L homeolog antikoerper, Topbp1 antikoerper, topbp1 antikoerper, TOPBP1 antikoerper, MEI1 antikoerper, topbp1.L antikoerper

Hintergrund: This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands.

Molekulargewicht: 170679

Gen-ID: 11073

NCBI Accession: NP_008958

UniProt: Q92547

Pathways: Chromatin Binding