PRKAG2 Antikörper (C-Term)

Produktnummer ABIN1574210

Produktdetails anti-PRKAG2 Antikörper

Target: PRKAG2 (Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2))

Bindungsspezifität: C-Term

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRKAG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: AMPKgamma2 Antibody, pAb, Rabbit detects human endogenous AMPKgamma2 and does not cross-react with AMPKgamma1 and AMPKgamma3. It is predicted to react with mouse and rat AMPKgamma2 according to sequence homology.

Kreuzreaktivität (Details): AMPKγ2 Antibody, pAb, Rabbit detects human endogenous AMPKγ2 and does not cross-react with AMPKγ1 and AMPKγ3. It is predicted to react with mouse and rat AMPKγ2 according to sequence homology.

Aufreinigung: Immunoaffinity chromatography

Immunogen: KLH-coupled synthetic peptide from C-terminal of human AMPKγ2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Western blot: 0.5-1 µg/mL Other Applications: User optimized

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4, containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Details zu PRKAG2

Target: PRKAG2 (Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2))

Andere Bezeichnung: AMPKgamma2 (PRKAG2 Produkte)

Synonyme: MGC82938 antikoerper, PRKAG2 antikoerper, si:ch211-230l11.1 antikoerper, si:dkey-217f4.2 antikoerper, AAKG antikoerper, AAKG2 antikoerper, CMH6 antikoerper, H91620p antikoerper, WPWS antikoerper, 2410051C13Rik antikoerper, AI854673 antikoerper, protein kinase AMP-activated non-catalytic subunit gamma 2 antikoerper, protein kinase, AMP-activated, gamma 2 non-catalytic subunit L homeolog antikoerper, 5'-AMP-activated protein kinase subunit gamma-2 antikoerper, protein kinase, AMP-activated, gamma 2 non-catalytic subunit b antikoerper, protein kinase, AMP-activated, gamma 2 non-catalytic subunit antikoerper, Prkag2 antikoerper, PRKAG2 antikoerper, prkag2.L antikoerper, LOC504219 antikoerper, prkag2b antikoerper, prkag2 antikoerper

Hintergrund: AMP-activated protein kinase (AMPK) plays an important role in the regulation of energy homeostasis. It is activated by an elevated AMP/ATP ratio caused by cellular and environmental stress, such as heat shock, hypoxia, and ischemia. AMPK is a heterotrimeric complex composed of a catalytic alpha subunit and regulatory beta and gamma subunits, each of which is encoded by two or three distinct genes (alpha1, alpha2, beta1, beta2, gamma1, gamma2, gamma3). AMPKgamma2 Antibody, pAb, Rabbit is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of human AMPKgamma2 (Swiss Prot: Q9UGJ0).

Pathways: AMPK Signaling, Cellular Glucan Metabolic Process, Ribonucleoside Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Warburg Effekt