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beta Amyloid Antikörper

Abeta Reaktivität: Human WB, IHC, IF, ICC Wirt: Maus Monoclonal AB9 unconjugated
Produktnummer ABIN1580412
  • Target Alle beta Amyloid (Abeta) Antikörper anzeigen
    beta Amyloid (Abeta) (Amyloid beta (Abeta))
    Reaktivität
    • 71
    • 22
    • 15
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 41
    • 30
    • 2
    • 1
    Maus
    Klonalität
    • 38
    • 31
    • 1
    Monoklonal
    Konjugat
    • 64
    • 5
    • 2
    • 1
    • 1
    • 1
    Dieser beta Amyloid Antikörper ist unkonjugiert
    Applikation
    • 52
    • 48
    • 31
    • 18
    • 14
    • 13
    • 9
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Aufreinigung
    affinity purified antibody
    Klon
    AB9
    Isotyp
    IgG2a
    Top Product
    Discover our top product Abeta Primärantikörper
  • Applikationshinweise
    The antibody solution can be used at dilutions of 1:1,000 or higher in immunofluorescence experiments. In western blotting using chemiluminescence it can be used at dilutions of 1:1,000-2,000.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 4°C short term or -20°C long term.
  • Target
    beta Amyloid (Abeta) (Amyloid beta (Abeta))
    Abstract
    Abeta Produkte
    Synonyme
    AAA antikoerper, ABETA antikoerper, ABPP antikoerper, AD1 antikoerper, APPI antikoerper, CTFgamma antikoerper, CVAP antikoerper, PN-II antikoerper, PN2 antikoerper, aaa antikoerper, abeta antikoerper, abpp antikoerper, ad1 antikoerper, appi antikoerper, ctfgamma antikoerper, cvap antikoerper, pn2 antikoerper, Abeta antikoerper, Abpp antikoerper, Adap antikoerper, Ag antikoerper, Cvap antikoerper, E030013M08Rik antikoerper, betaApp antikoerper, amyloid beta precursor protein antikoerper, amyloid beta (A4) precursor protein antikoerper, APP antikoerper, app antikoerper, App antikoerper
    Hintergrund
    Alzheimer's disease (AD) is a serious and common age related dementia which is characterized by the formation of senile plaques and neurofibrillary tangles. Senile plaques are extracellular accumulations of insoluble proteins found in cortical regions. A major component of senile plaques is beta,-amyloid, a.k.a. Abeta, a peptide predominantly of 42 or 40 amino acids. The Abeta, peptide is derived from a section of the membrane spanning domain and the immediate extracellular region of a much larger protein called the amyloid precursor protein (APP). This is an abundant protein of poorly understood function. The Abeta, peptides are generated by the activity of proteases called secretases, specifically the beta, and gamma, secretases. Certain mutations in the APP gene are associated with familial forms of AD, as are mutations in the genes encoding proteins forming the secretase enzymes, in line with the hypothesis that Abeta, accumulation is central to the AD disease process. Our antibody recognizes amino acids 1-16 of the Abeta, peptide and works well on western blots, on formalin fixed sections and as a capture reagent in ELISA. It was originally developed in the Mayo Clinic in Jacksonville in the laboratory of Dr. Todd Golde.
    Pathways
    Inflammasome
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