PARL Antikörper (C-Term)

Produktnummer ABIN1607894

Hersteller Produkt- Nr.: 600-401-j27

Produktdetails anti-PARL Antikörper

Target: PARL (Presenilin Associated, Rhomboid-Like (PARL))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Huhn, Primate

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Fluorescence Microscopy (FM)

Hersteller Produkt- Nr.: 600-401-j27

Hersteller: Rockland

Verwendungszweck: PARL Antibody

Kreuzreaktivität (Details): This antibody is specific towards PARL.

Produktmerkmale: Synonyms: rabbit anti-PARL antibody, p-beta, Pbeta, presenilin associated rhomboid-like protein mitochondrial, PRO2207, Mitochondrial intramembrane cleaving protease PARL, PSARL

Aufreinigung: Anti-PARL was affinity purified from monospecific antiserum by immunoaffinity chromatography.

Sterilität: Sterile filtered

Immunogen:

Immunogen: PARL affinity purified antibody was prepared from whole rabbit serum produced by repeated immunization from a synthetic peptide corresponding to the C terminus region of human PARL.

Immunogen Type: Conjugated Peptide

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry Dilution: 1:100-1:500

Application Note: Anti-PARL antibody is useful for ELISA and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~42.2 kDa corresponding to the appropriate cell lysate or extract.

Western Blot Dilution: 1 μg/mL

ELISA Dilution: 1:20,000 - 1:60,000

IF Microscopy Dilution: 1:100-1:500

Other: User Optimized

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.86 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Preservative: None

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 6 months

Details zu PARL

Target: PARL (Presenilin Associated, Rhomboid-Like (PARL))

Andere Bezeichnung: PARL (PARL Produkte)

Hintergrund: Background: PARL (presenilin associated, rhomboid-like) encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. Anti-PARL antibodies are ideal for researchers interested in Apoptosis, Alzheimer's Research, Neuroscience, and Mitochondrial Fusion Proteins research.

Gen-ID: 55486

NCBI Accession: NP_061092

UniProt: Q9H300

Pathways: Autophagie