NCR1 Antikörper

Produktnummer ABIN165440

Produktdetails anti-NCR1 Antikörper

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NCR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Aufreinigung: The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography

Immunogen: Recombinant NKp46, Accession / GI number: NP_004820

Klon: N1D9

Isotyp: Kappa

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1mg/ml

Buffer: In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu NCR1

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Andere Bezeichnung: NKp46 (NCR1 Produkte)

Synonyme: CD335 antikoerper, LY94 antikoerper, NK-p46 antikoerper, NKP46 antikoerper, Ly94 antikoerper, NKp46 antikoerper, KILR-1 antikoerper, Nk-p46 antikoerper, Nkp46 antikoerper, natural cytotoxicity triggering receptor 1 antikoerper, NCR1 antikoerper, Ncr1 antikoerper

Hintergrund: A natural cytotoxicity receptor (NCR), NKp46, is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 residue stalk resion, a type I transmembrane domain, and a short cytoplasmic tail. NKp46 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NKp46 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.

Pathways: Regulation of Leukocyte Mediated Immunity