PPM1A Antikörper

Produktnummer ABIN165454

Produktdetails anti-PPM1A Antikörper

Target: PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PPM1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Aufreinigung: The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography

Immunogen: Recombinant PP2Ca, Accession / GI number: NP_808821

Klon: P6c7

Isotyp: Kappa

Anwendungsinformationen

Applikationshinweise: Recommended dilution 1:250

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1mg/ml

Buffer: In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu PPM1A

Target: PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))

Andere Bezeichnung: PP2C alpha (PPM1A Produkte)

Hintergrund: Protein phosphatase 2C (PP2C) is a Mn2+- or Mg2+-dependent protein serine/threonine phosphatase that inhibits the human stress-responsive p38 and JNK MAPK pathways and regulates cellular stress response in eukaryotes. The PPM(metal-dependent protein phosphatase) family of Ser/Thr protein phosphatases have recently been shown to down-regulate the stress response pathways in eukaryotes. Within the stress pathway, key signaling kinases, which are activated by protein phosphorylation, have been proposed as the in vivo substrates of PP2C, the prototypical member of the PPM family.