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PUMA Antikörper

BBC3 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Monoclonal unconjugated
Produktnummer ABIN7101572
  • Target Alle PUMA (BBC3) Antikörper anzeigen
    PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
    Reaktivität
    • 92
    • 40
    • 38
    • 16
    Human
    Wirt
    • 89
    • 6
    • 1
    Kaninchen
    Klonalität
    • 81
    • 15
    Monoklonal
    Konjugat
    • 48
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PUMA Antikörper ist unkonjugiert
    Applikation
    • 77
    • 34
    • 29
    • 21
    • 16
    • 14
    • 13
    • 12
    • 9
    • 7
    • 5
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Monoclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    A synthesized peptide derived from human PUMA
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
    Andere Bezeichnung
    BBC3 (BBC3 Produkte)
    Synonyme
    BBC3 antikoerper, Puma antikoerper, JFY-1 antikoerper, JFY1 antikoerper, PUMA antikoerper, PUMA/JFY1 antikoerper, BCL2 binding component 3 antikoerper, Bcl-2 binding component 3 antikoerper, BBC3 antikoerper, Bbc3 antikoerper, bbc3 antikoerper
    Hintergrund
    This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011],JFY-1, JFY1, PUMA,Apoptosis,Apoptosis_Mitochondrial Control of Apoptosis,Cell Biology & Developmental Biology,Endocrine & Metabolism,Neurodegenerative Diseases,Neuroscience,BBC3
    Molekulargewicht
    18 kDa
    Gen-ID
    27113
    UniProt
    Q96PG8, Q9BXH1
    Pathways
    p53 Signalweg, Positive Regulation of Endopeptidase Activity
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