PUMA Antikörper
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- Target Alle PUMA (BBC3) Antikörper anzeigen
- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser PUMA Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Monoclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- A synthesized peptide derived from human PUMA
- Isotyp
- IgG
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- Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
- Andere Bezeichnung
- BBC3 (BBC3 Produkte)
- Synonyme
- BBC3 antikoerper, Puma antikoerper, JFY-1 antikoerper, JFY1 antikoerper, PUMA antikoerper, PUMA/JFY1 antikoerper, BCL2 binding component 3 antikoerper, Bcl-2 binding component 3 antikoerper, BBC3 antikoerper, Bbc3 antikoerper, bbc3 antikoerper
- Hintergrund
- This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011],JFY-1, JFY1, PUMA,Apoptosis,Apoptosis_Mitochondrial Control of Apoptosis,Cell Biology & Developmental Biology,Endocrine & Metabolism,Neurodegenerative Diseases,Neuroscience,BBC3
- Molekulargewicht
- 18 kDa
- Gen-ID
- 27113
- UniProt
- Q96PG8, Q9BXH1
- Pathways
- p53 Signalweg, Positive Regulation of Endopeptidase Activity
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