GTPBP4 Antikörper (AA 385-634)

Produktnummer ABIN1680142

Produktdetails anti-GTPBP4 Antikörper

Target: GTPBP4 (GTP Binding Protein 4 (GTPBP4))

Bindungsspezifität: AA 385-634

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GTPBP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: RKRMETEESR KKRERDLELE MGDDYILDLQ KYWDLMNLSE KHDKIPEIWE GHNIADYIDP AIMKKLEELE KEEELRTAAG EYDSVSESED EEMLEIRQLA KQIREKKKLK ILESKEKNTQ GPRMPRTAKK VQRTVLEKEM RSLGVDMDDK DDAHYAVQAR RSRSITRKRK REDSAPPSSV ARSGSCSRTP RDVSGLRDVK MVKKAKTMMK NAQKKMNRLG KKGEADRHVF DMKPKHLLSG KRKAGKKDRR

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 385-634 of human GTPBP4 (NP_036473.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GTPBP4

Target: GTPBP4 (GTP Binding Protein 4 (GTPBP4))

Andere Bezeichnung: GTPBP4 (GTPBP4 Produkte)

Synonyme: CRFG antikoerper, NGB antikoerper, NOG1 antikoerper, 2610028C09Rik antikoerper, Crfg antikoerper, Gtpbp3 antikoerper, Nog1 antikoerper, fi28d07 antikoerper, zgc:55757 antikoerper, wu:fi28d07 antikoerper, xgb antikoerper, GTP binding protein 4 antikoerper, GTP binding protein 4 L homeolog antikoerper, GTPBP4 antikoerper, Gtpbp4 antikoerper, gtpbp4 antikoerper, CC1G_14285 antikoerper, gtpbp4.L antikoerper

Hintergrund: GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.,GTPBP4,CRFG,NGB,NOG1,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Tumor suppressors,Signal Transduction,GTPBP4

Molekulargewicht: 60 kDa/68 kDa/73 kDa

Gen-ID: 23560

UniProt: Q9BZE4