Ubiquitin B Antikörper
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- Target Alle Ubiquitin B (UBB) Antikörper anzeigen
- Ubiquitin B (UBB)
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser Ubiquitin B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Monoclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- A synthesized peptide derived from human K48-linkage Specific Ubiquitin
- Isotyp
- IgG
- Top Product
- Discover our top product UBB Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000, IF,1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Ubiquitin B (UBB)
- Andere Bezeichnung
- UBB (UBB Produkte)
- Hintergrund
- This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],HEL-S-50,Apoptosis,Apoptosis_Mitochondrial Control of Apoptosis,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,Neurodegenerative Diseases,Neurodegenerative Diseases_Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimers Disease,Neuroscience,Ubiquitin,Ubiquitin_Ubiquitin-Proteasome Signaling Pathway,UBB
- Gen-ID
- 7314
- UniProt
- P0CG47
- Pathways
- Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, Toll-Like Receptors Cascades, Synthesis of DNA, Autophagie, EGFR Downregulation, Ubiquitin Proteasome Pathway
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