MYCN Antikörper (AA 168-267)

Produktnummer ABIN1680957

Produktdetails anti-MYCN Antikörper

Target: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Bindungsspezifität: AA 168-267

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYCN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: AGRAGAALPA ELAHPAAECV DPAVVFPFPV NKREPAPVPA APASAPAAGP AVASGAGIAA PAGAPGVAPP RPGGRQTSGG DHKALSTSGE DTLSDSDDED

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 168-267 of human MYCN (NP_005369.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-MYCN Antikörper (ABIN1680957)

Chang, Yang, Zheng, Li, Nie: "Arsenic trioxide inhibits cancer stem-like cells via down-regulation of Gli1 in lung cancer." in: American journal of translational research, Vol. 8, Issue 2, pp. 1133-43, (2016) (PubMed).

Details zu MYCN

Target: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Andere Bezeichnung: MYCN (MYCN Produkte)

Synonyme: MODED antikoerper, MYCNOT antikoerper, N-myc antikoerper, NMYC antikoerper, ODED antikoerper, bHLHe37 antikoerper, Nmyc antikoerper, Nmyc-1 antikoerper, Nmyc1 antikoerper, c-nmyc antikoerper, Nmuc1 antikoerper, fb57a02 antikoerper, nmyc1 antikoerper, wu:fb57a02 antikoerper, zgc:85706 antikoerper, XN-myc antikoerper, XNmyc antikoerper, mycn antikoerper, mycn-a antikoerper, mycn-b antikoerper, mycna antikoerper, xN-myc1 antikoerper, MYCN proto-oncogene, bHLH transcription factor antikoerper, v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog antikoerper, v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived antikoerper, olfactory receptor 8S1 antikoerper, MYCN proto-oncogene, bHLH transcription factor S homeolog antikoerper, MYCN antikoerper, Mycn antikoerper, LOC515887 antikoerper, mycn antikoerper, mycn.S antikoerper

Hintergrund: This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.,MODED,N-myc,NMYC,ODED,bHLHe37,MYCN,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,MAPK-Erk Signaling Pathway,MYCN

Molekulargewicht: 49 kDa

Gen-ID: 4613

UniProt: P04198