NBR1 Antikörper

Produktnummer ABIN1680974

Produktdetails anti-NBR1 Antikörper

Target: NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NBR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Kreuzreaktivität: Human, Affe, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant protein of human NBR1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100,IP,1:20 - 1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NBR1

Target: NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

Andere Bezeichnung: NBR1 (NBR1 Produkte)

Hintergrund: The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.,NBR1,1A1-3B,IAI3B,M17S2,MIG19,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial Control of Autophagy,NBR1

Molekulargewicht: 103 kDa/107 kDa

Gen-ID: 4077

UniProt: Q14596

Pathways: Autophagie