Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and a regulatory subunit. The protein encoded by this gene represents a regulatory subunit of PI3K. The encoded protein contains two SH2 domains through which it binds activated protein tyrosine kinases to regulate their activity. [provided by RefSeq, Jun 2016],p55, p55-GAMMA, p55PIK,AMPK Signaling Pathway,Angiogenesis,Apoptosis,Apoptosis_Inhibition of Apoptosis,Apoptosis_Mitochondrial Control of Apoptosis,Cardiovascular,Cell Adhesion,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Actins,Cytoskeleton_Microtubules,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,ErbB-HER Signaling Pathway,ESC Pluripotency and Differentiation,G protein signaling,IL-6 Receptor Signaling Pathway,Immunology & Inflammation,Kinase,Lipid Metabolism,MAPK-Erk Signaling Pathway,MAPK-JNK Signaling Pathway,mTOR Signaling Pathway,NF-kB Signaling Pathway,PI3K-Akt Signaling Pathway,Protein Kinase C Signaling Pathway Pathway,Signal Transduction,T Cell Receptor Signaling Pathway,TGF-b-Smad Signaling Pathway,Translation Control,Translational Control_Regulation of eIF4 and p70 S6 Kinase,Warburg Effect,PIK3R3