POLG Antikörper

Produktnummer ABIN7101417

Produktdetails anti-POLG Antikörper

Target: POLG (Polymerase (DNA Directed), gamma (POLG))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser POLG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human DNA Polymerase gamma

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu POLG

Target: POLG (Polymerase (DNA Directed), gamma (POLG))

Andere Bezeichnung: POLG (POLG Produkte)

Synonyme: POLG antikoerper, MDP1 antikoerper, MIRAS antikoerper, MTDPS4A antikoerper, MTDPS4B antikoerper, PEO antikoerper, POLG1 antikoerper, POLGA antikoerper, SANDO antikoerper, SCAE antikoerper, AA409516 antikoerper, PolgA antikoerper, polymerase (DNA) gamma, catalytic subunit L homeolog antikoerper, DNA polymerase gamma, catalytic subunit antikoerper, polymerase (DNA directed), gamma antikoerper, polg.L antikoerper, Polg antikoerper, POLG antikoerper, polg antikoerper

Substanzklasse: Viral Protein

Hintergrund: Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],MDP1, MIRAS, MTDPS4A, MTDPS4B, PEO, POLG1, POLGA, SANDO, SCAE,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,Mitochondrial metabolism,Mitochondrial metabolism_Mitochondrial Biogenesis,Nucleotide metabolism,Nucleotide metabolism_Molecular processes,POLG

Molekulargewicht: 140 kDa

Gen-ID: 5428

UniProt: P54098