STAT4 Antikörper

Produktnummer ABIN7101700

Produktdetails anti-STAT4 Antikörper

Target: STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser STAT4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human STAT4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu STAT4

Target: STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))

Andere Bezeichnung: STAT4 (STAT4 Produkte)

Synonyme: SLEB11 antikoerper, signal transducer and activator of transcription 4 antikoerper, STAT4 antikoerper, stat4 antikoerper, Stat4 antikoerper

Hintergrund: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011],SLEB11,Epigenetics & Nuclear Signaling,ErbB-HER Signaling Pathway,IL-6 Receptor Signaling Pathway,Immunology & Inflammation,Protein phosphorylation,Signal Transduction,Transcription Factors,STAT4

Molekulargewicht: 86 kDa

Gen-ID: 6775

UniProt: Q14765

Pathways: JAK-STAT Signalweg