OAS1 Antikörper (AA 1-364)

Produktnummer ABIN1681145

Produktdetails anti-OAS1 Antikörper

Target: OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))

Bindungsspezifität: AA 1-364

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OAS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MMDLRNTPAK SLDKFIEDYL LPDTCFRMQI NHAIDIICGF LKERCFRGSS YPVCVSKVVK GGSSGKGTTL RGRSDADLVV FLSPLTTFQD QLNRRGEFIQ EIRRQLEACQ RERAFSVKFE VQAPRWGNPR ALSFVLSSLQ LGEGVEFDVL PAFDALGQLT GGYKPNPQIY VKLIEECTDL QKEGEFSTCF TELQRDFLKQ RPTKLKSLIR LVKHWYQNCK KKLGKLPPQY ALELLTVYAW ERGSMKTHFN TAQGFRTVLE LVINYQQLCI YWTKYYDFKN PIIEKYLRRQ LTKPRPVILD PADPTGNLGG GDPKGWRQLA QEAEAWLNYP CFKNWDGSPV SSWILLVRPP ASSLPFIPAP LHEA

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-364 of human OAS1 (NP_002525.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu OAS1

Target: OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))

Andere Bezeichnung: OAS1 (OAS1 Produkte)

Synonyme: OAS1 antikoerper, IFI-4 antikoerper, OIAS antikoerper, OIASI antikoerper, L3 antikoerper, Pp2a2 antikoerper, 2',5'-oligoadenylate synthetase 1 antikoerper, 2'-5'-oligoadenylate synthetase 1 antikoerper, 2'-5' oligoadenylate synthetase 1A antikoerper, protein phosphatase 2 catalytic subunit beta antikoerper, OAS1 antikoerper, Oas1a antikoerper, Ppp2cb antikoerper, Oas1 antikoerper

Hintergrund: This gene is induced by interferons and encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein activates latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection and diabetes mellitus, type 1. A disease-associated allele in a splice acceptor site influences the production of the p46 splice isoform. This gene is located in a cluster of related genes on chromosome 12.,OAS1,E18/E16,IFI-4,OIAS,OIASI,Epigenetics & Nuclear Signaling,OAS1

Molekulargewicht: 41 kDa/43 kDa/46 kDa/47 kDa

Gen-ID: 4938

UniProt: P00973

Pathways: Hepatitis C