RAPGEF4 Antikörper (AA 1-210)

Produktnummer ABIN1682483

Produktdetails anti-RAPGEF4 Antikörper

Target: RAPGEF4 (Rap Guanine Nucleotide Exchange Factor (GEF) 4 (RAPGEF4))

Bindungsspezifität: AA 1-210

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAPGEF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MLYKKYRQYM AGLLAPPYGV METGSNNDRI PDKENTPLIE PHVPLRPANT ITKVPSEKIL RAGKILRNAI LSRAPHMIRD RKYHLKTYRQ CCVGTELVDW MMQQTPCVHS RTQAVGMWQV LLEDGVLNHV DQEHHFQDKY LFYRFLDDEH EDAPLPTEEE KKECDEELQD TMLLLSQMGP DAHMRMILRK PPGQRTVDDL EIIYEELLHI

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human RAPGEF4 (NP_001093867.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RAPGEF4

Target: RAPGEF4 (Rap Guanine Nucleotide Exchange Factor (GEF) 4 (RAPGEF4))

Andere Bezeichnung: RAPGEF4 (RAPGEF4 Produkte)

Hintergrund: Guanine nucleotide exchange factor (GEF for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2 (By similarity.,RAPGEF4,CAMP-GEFII,CGEF2,EPAC,EPAC 2,EPAC2,Nbla00496,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,MAPK-Erk Signaling Pathway,Endocrine & Metabolism,Immunology & Inflammation,RAPGEF4

Molekulargewicht: 79 kDa/96 kDa/98 kDa/99 kDa/115 kDa

Gen-ID: 11069

UniProt: Q8WZA2

Pathways: Hormone Transport, Smooth Muscle Cell Migration