Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

SMC5 Antikörper (AA 872-1101)

SMC5 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1682829
  • Target Alle SMC5 Antikörper anzeigen
    SMC5 (Structural Maintenance of Chromosomes 5 (SMC5))
    Bindungsspezifität
    • 15
    • 5
    • 3
    • 1
    • 1
    AA 872-1101
    Reaktivität
    • 34
    • 18
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 32
    • 1
    • 1
    Kaninchen
    Klonalität
    • 34
    Polyklonal
    Konjugat
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SMC5 Antikörper ist unkonjugiert
    Applikation
    • 22
    • 13
    • 13
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    LTEERSRASC FTGLNPTIVQ EYTKREEEIE QLTEELKGKK VELDQYRENI SQVKERWLNP LKELVEKINE KFSNFFSSMQ CAGEVDLHTE NEEDYDKYGI RIRVKFRSST QLHELTPHHQ SGGERSVSTM LYLMALQELN RCPFRVVDEI NQGMDPINER RVFEMVVNTA CKENTSQYFF ITPKLLQNLP YSEKMTVLFV YNGPHMLEPN TWNLKAFQRR RRRITFTQPS
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 872-1101 of human SMC5 (NP_055925.2).
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:1000 - 1:3000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    SMC5 (Structural Maintenance of Chromosomes 5 (SMC5))
    Andere Bezeichnung
    SMC5 (SMC5 Produkte)
    Synonyme
    F1N13.60 antikoerper, F1N13_60 antikoerper, structural maintenance of chromosomes 5 antikoerper, SMC-5 antikoerper, SMC5L1 antikoerper, MLZ-453 antikoerper, Smc5l1 antikoerper, mKIAA0594 antikoerper, mSMC5 antikoerper, structural maintenance of chromosomes 5 antikoerper, structural maintenance of chromosomes 5 S homeolog antikoerper, SMC5 antikoerper, smc5 antikoerper, Smc5 antikoerper, smc5.S antikoerper
    Hintergrund
    Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres cell lines and mediates sumoylation of shelterin complex (telosome components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs. Required for recruitment of telomeres to PML nuclear bodies. Required for sister chromatid cohesion during prometaphase and mitotic progression, the function seems to be independent of SMC6. SMC5-SMC6 complex may prevent transcription of episomal DNA, such as circular viral DNA genome.,SMC5,SMC5L1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,SMC5
    Molekulargewicht
    128 kDa
    Gen-ID
    23137
    UniProt
    Q8IY18
Sie sind hier:
Kundenservice