SNAIL Antikörper (AA 1-100)

Produktnummer ABIN1682836

Produktdetails anti-SNAIL Antikörper

Target: SNAIL (SNAI1)

Bindungsspezifität: AA 1-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNAIL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: MPRSFLVRKP SDPNRKPNYS ELQDSNPEFT FQQPYDQAHL LAAIPPPEIL NPTASLPMLI WDSVLAPQAQ PIAWASLRLQ ESPRVAELTS LSDEDSGKGS

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Snail (NP_005976.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-SNAIL Antikörper (ABIN1682836)

Yang, Qiu, Xiao, Hu, Liu, Chen, Huang, Li, Li, Zhang, Ding, Xiang: "AP-2β inhibits hepatocellular carcinoma invasion and metastasis through Slug and Snail to suppress epithelial-mesenchymal transition." in: Theranostics, Vol. 8, Issue 13, pp. 3707-3721, (2018) (PubMed).

Wang, Dong, Wang, Li, Dong, Jeyalatha, Wu, Shen, Yang, Chen, Xue, Liu, Li: "Epithelial dysplasia in pterygium postoperative granuloma." in: Experimental eye research, Vol. 175, pp. 199-206, (2018) (PubMed).

Du, Fang, Chen, Teng, Xiao, Xie, Jin, Wang: "Effect of silencing the T‑Box transcription factor TBX2 in prostate cancer PC3 and LNCaP cells." in: Molecular medicine reports, Vol. 16, Issue 5, pp. 6050-6058, (2018) (PubMed).

Zhan, Chen, Chen: "Knockdown of FUT3 disrupts the proliferation, migration, tumorigenesis and TGF-β induced EMT in pancreatic cancer cells." in: Oncology letters, Vol. 16, Issue 1, pp. 924-930, (2018) (PubMed).

Chen, Zheng, Liu, Shi, Qi: "Periostin activates pathways involved in epithelial-mesenchymal transition in adamantinomatous craniopharyngioma." in: Journal of the neurological sciences, Vol. 360, pp. 49-54, (2016) (PubMed).

Xu, Zhu, Zhao, Chen, Zhang, Yuan, Deng, Dou, Wang, Huang, Chen, Jiang, Yu: "Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors." in: Oncotarget, Vol. 6, Issue 2, pp. 979-94, (2015) (PubMed).

Details zu SNAIL

Target: SNAIL (SNAI1)

Andere Bezeichnung: SNAI1 (SNAI1 Produkte)

Hintergrund: The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2.,SNAI1,SLUGH2,SNA,SNAH,SNAIL,SNAIL1,dJ710H13.1,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Cardiovascular,Heart,Cardiogenesis,SNAI1

Molekulargewicht: 29 kDa

Gen-ID: 6615

UniProt: O95863

Pathways: Negative Regulation of intrinsic apoptotic Signaling