TIE1 Antikörper (AA 350-600)

Produktnummer ABIN1683033

Produktdetails anti-TIE1 Antikörper

Target: TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))

Bindungsspezifität: AA 350-600

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: IPQILNMASE LEFNLETMPR INCAAAGNPF PVRGSIELRK PDGTVLLSTK AIVEPEKTTA EFEVPRLVLA DSGFWECRVS TSGGQDSRRF KVNVKVPPVP LAAPRLLTKQ SRQLVVSPLV SFSGDGPIST VRLHYRPQDS TMDWSTIVVD PSENVTLMNL RPKTGYSVRV QLSRPGEGGE GAWGPPTLMT TDCPEPLLQP WLEGWHVEGT DRLRVSWSLP LVPGPLVGDG FLLRLWDGTR GQERRENVSS P

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 350-600 of human TIE1 (NP_005415.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TIE1

Target: TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))

Andere Bezeichnung: TIE1 (TIE1 Produkte)

Hintergrund: This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,TIE1,JTK14,TIE,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,Stem Cells,Endothelial Progenitors,Cardiovascular,TIE1

Molekulargewicht: 34 kDa/40 kDa/125 kDa

Gen-ID: 7075

UniProt: P35590

Pathways: RTK Signalweg