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STING/TMEM173 Antikörper (AA 170-379)

TMEM173 Reaktivität: Human WB, IHC, IP, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6220283
  • Target Alle STING/TMEM173 (TMEM173) Antikörper anzeigen
    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
    Bindungsspezifität
    • 15
    • 13
    • 11
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 170-379
    Reaktivität
    • 66
    • 25
    • 21
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 79
    • 5
    Kaninchen
    Klonalität
    • 66
    • 18
    Polyklonal
    Konjugat
    • 42
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser STING/TMEM173 Antikörper ist unkonjugiert
    Applikation
    • 48
    • 26
    • 17
    • 17
    • 13
    • 13
    • 12
    • 8
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
    Sequenz
    LILPELQARI RTYNQHYNNL LRGAVSQRLY ILLPLDCGVP DNLSMADPNI RFLDKLPQQT GDHAGIKDRV YSNSIYELLE NGQRAGTCVL EYATPLQTLF AMSQYSQAGF SREDRLEQAK LFCRTLEDIL ADAPESQNNC RLIAYQEPAD DSSFSLSQEV LRHLRQEEKE EVTVGSLKTS AVPSTSTMSQ EPELLISGME KPLPLRTDFS
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 170-379 of human STING/TMEM173 (NP_938023.1).
    Isotyp
    IgG
    Top Product
    Discover our top product TMEM173 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
    Andere Bezeichnung
    STING (TMEM173 Produkte)
    Hintergrund
    This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.,TMEM173,ERIS,MITA,MPYS,NET23,SAVI,STING,hMITA,hSTING,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Immunology & Inflammation,Cytokines,Interferons,Cell Intrinsic Innate Immunity Signaling Pathway,STING
    Molekulargewicht
    42 kDa
    Gen-ID
    340061
    UniProt
    Q86WV6
    Pathways
    Activation of Innate immune Response
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