tara antikoerper, DFNB28 antikoerper, TARA antikoerper, dJ37E16.4 antikoerper, AI428493 antikoerper, EST478828 antikoerper, Tara antikoerper, mKIAA1662 antikoerper, TRIO and F-actin binding protein antikoerper, TRIO and F-actin-binding protein antikoerper, TRIO and F-actin binding protein L homeolog antikoerper, TRIO and F-actin binding protein-like antikoerper, TRIOBP antikoerper, LOC100354753 antikoerper, triobp.L antikoerper, TRIOBPL antikoerper, Triobp antikoerper
Hintergrund
This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).,TRIOBP,DFNB28,HRIHFB2122,TAP68,TARA,dJ37E16.4,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Neuroscience,TRIOBP