UBC Antikörper (AA 1-100)

Produktnummer ABIN1683190

Produktdetails anti-UBC Antikörper

Target: UBC (Ubiquitin C (UBC))

Bindungsspezifität: AA 1-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MQIFVKTLTG KTITLEVEPS DTIENVKAKI QDKEGIPPDQ QRLIFAGKQL EDGRTLSDYN IQKESTLHLV LRLRGGMQIF VKTLTGKTIT LEVEPSDTIE

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human UBC (NP_066289.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:2000,IHC,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-UBC Antikörper (ABIN1683190)

Li, Chan, Yu, Bei, Chen, Zhou, Cheng, Chen, Ziegler, Rowe, Das, Xiao: "miR-29b contributes to multiple types of muscle atrophy." in: Nature communications, Vol. 8, pp. 15201, (2018) (PubMed).

Wang, Hu, Xiao, Wang, Liu, Xu, Shi, Jiang, Huang, Li, Liu, Qing: "Stabilization of Notch1 by the Hsp90 Chaperone Is Crucial for T-Cell Leukemogenesis." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 23, Issue 14, pp. 3834-3846, (2018) (PubMed).

Xiao, Yue, Su, Ren, Jiang, Li, Hu, Du, Liu, Qing: "Polo-like Kinase-1 Regulates Myc Stabilization and Activates a Feedforward Circuit Promoting Tumor Cell Survival." in: Molecular cell, Vol. 64, Issue 3, pp. 493-506, (2017) (PubMed).

Details zu UBC

Target: UBC (Ubiquitin C (UBC))

Andere Bezeichnung: UBC (UBC Produkte)

Synonyme: HMG20 antikoerper, 2700054O04Rik antikoerper, AI194771 antikoerper, Rps27a antikoerper, TI-225 antikoerper, Uba52 antikoerper, Ubb antikoerper, ubiquitin C antikoerper, UBC antikoerper, Ubc antikoerper

Hintergrund: This gene represents a ubiquitin gene, ubiquitin C. The encoded protein is a polyubiquitin precursor. Conjugation of ubiquitin monomers or polymers can lead to various effects within a cell, depending on the residues to which ubiquitin is conjugated. Ubiquitination has been associated with protein degradation, DNA repair, cell cycle regulation, kinase modification, endocytosis, and regulation of other cell signaling pathways.,UBC,HMG20,ubiquitin C,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,UBC

Molekulargewicht: 77 kDa

Gen-ID: 7316

UniProt: P0CG48

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, Toll-Like Receptors Cascades, Synthesis of DNA, EGFR Downregulation, Ubiquitin Proteasome Pathway