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WISP1 Antikörper (AA 158-367)

WISP1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1683290
  • Target Alle WISP1 Antikörper anzeigen
    WISP1 (WNT1 Inducible Signaling Pathway Protein 1 (WISP1))
    Bindungsspezifität
    • 15
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 158-367
    Reaktivität
    • 40
    • 26
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 54
    • 5
    • 1
    • 1
    Kaninchen
    Klonalität
    • 57
    • 4
    Polyklonal
    Konjugat
    • 26
    • 9
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser WISP1 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 21
    • 20
    • 13
    • 13
    • 8
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    LRVRPPRLWC PHPRRVSIPG HCCEQWVCED DAKRPRKTAP RDTGAFDAVG EVEAWHRNCI AYTSPWSPCS TSCGLGVSTR ISNVNAQCWP EQESRLCNLR PCDVDIHTLI KAGKKCLAVY QPEASMNFTL AGCISTRSYQ PKYCGVCMDN RCCIPYKSKT IDVSFQCPDG LGFSRQVLWI NACFCNLSCR NPNDIFADLE SYPDFSEIAN
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 158-367 of human WISP1 (NP_003873.1).
    Isotyp
    IgG
    Top Product
    Discover our top product WISP1 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    WISP1 (WNT1 Inducible Signaling Pathway Protein 1 (WISP1))
    Andere Bezeichnung
    WISP1 (WISP1 Produkte)
    Synonyme
    CCN4 antikoerper, WISP1c antikoerper, WISP1i antikoerper, WISP1tc antikoerper, WISP-1 antikoerper, WISP1 antikoerper, si:ch211-38f10.2 antikoerper, AW146261 antikoerper, Elm1 antikoerper, zgc:172276 antikoerper, WNT1 inducible signaling pathway protein 1 antikoerper, WNT1 inducible signaling pathway protein 1a antikoerper, WNT1-inducible-signaling pathway protein 1-like antikoerper, WNT1 inducible signaling pathway protein 1b antikoerper, WISP1 antikoerper, wisp1a antikoerper, Wisp1 antikoerper, LOC100627044 antikoerper, wisp1b antikoerper
    Hintergrund
    This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. It is expressed at a high level in fibroblast cells, and overexpressed in colon tumors. The encoded protein binds to decorin and biglycan, two members of a family of small leucine-rich proteoglycans present in the extracellular matrix of connective tissue, and possibly prevents the inhibitory activity of decorin and biglycan in tumor cell proliferation. It also attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase. It is 83 % identical to the mouse protein at the amino acid level. Multiple alternatively spliced transcript variants have been identified.,WISP1,CCN4,WISP1c,WISP1i,WISP1tc,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Stem Cells,WISP1
    Molekulargewicht
    13 kDa/16 kDa/21 kDa/30 kDa/40 kDa
    Gen-ID
    8840
    UniProt
    O95388
    Pathways
    WNT Signalweg, Growth Factor Binding
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