LRP4 Antikörper (AA 26-350)

Produktnummer ABIN1686627

Produktdetails anti-LRP4 Antikörper

Target: LRP4 (Low Density Lipoprotein Receptor-Related Protein 4 (LRP4))

Bindungsspezifität: AA 26-350

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LRP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: Detects the extracellular domain of LRP4 ~215 kDa. Degradation product can be seen at ~150 kDa.

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Protein G Purified

Immunogen: Fusion protein amino acids 26- 350 (extracellular N-terminus) of mouse LTP4

Klon: S207-27

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Kommentare:

1 μg/ml of ABIN1686627 was sufficient for detection of LRP4 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Details zu LRP4

Target: LRP4 (Low Density Lipoprotein Receptor-Related Protein 4 (LRP4))

Andere Bezeichnung: LRP4 (LRP4 Produkte)

Hintergrund: Potential cell surface endocytic receptor, which binds and internalizes extracellular ligands for degradation by lysosomes. It is involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway.

Gen-ID: 83469

NCBI Accession: NP_766256

UniProt: Q8VI56

Pathways: Skeletal Muscle Fiber Development