PDE8A Antikörper
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- Target Alle PDE8A Antikörper anzeigen
- PDE8A (phosphodiesterase 8A (PDE8A))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PDE8A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- The mouse monoclonal antibody EM-52 recognizes PDE8a (phosphodiesterase 8 A), an approximately 93 kDa intracellular enzyme that hydrolyzes cAMP to 5'AMP.
- Kreuzreaktivität (Details)
- Human
- Aufreinigung
- Purified by protein-A affinity chromatography.
- Reinheit
- > 95 % (by SDS-PAGE)
- Immunogen
- Human PDE8a
- Klon
- EM-52
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product PDE8A Primärantikörper
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- Applikationshinweise
- Western blotting: Recommended dilution: 1-2 μg/mL.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Handhabung
- Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- Target
- PDE8A (phosphodiesterase 8A (PDE8A))
- Andere Bezeichnung
- PDE8a (PDE8A Produkte)
- Synonyme
- PDE8A antikoerper, Pde8a antikoerper, HsT19550 antikoerper, AI551852 antikoerper, Pde8 antikoerper, RNPDE8A antikoerper, phosphodiesterase 8A antikoerper, PDE8A antikoerper, Pde8a antikoerper, pde8a antikoerper
- Hintergrund
- Phosphodiesterase 8A,PDE8a (high affinity cAMP-specific and IBMX-insensitive 3´,5´-cyclic phosphodiesterase 8 A) is a cyclic nucleotide phosphodiesterase, which hydrolyzes cAMP, an important regulator and mediator of multiple cellular responses to extracellular signals. It is expressed in a wide variety of tissues including testis, ovary, small intestine, and colon. It is not expressed e.g. in thymus. PDE8a is composed of C-terminal catalytic domain containing two putative divalent metal sites and an N-terminal regulatory domain.,HsT19550
- Gen-ID
- 5151
- UniProt
- O60658
- Pathways
- cAMP Metabolic Process
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