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PDE8A Antikörper

PDE8A Reaktivität: Human WB Wirt: Maus Monoclonal EM-52 unconjugated
Produktnummer ABIN1690735
  • Target Alle PDE8A Antikörper anzeigen
    PDE8A (phosphodiesterase 8A (PDE8A))
    Reaktivität
    • 46
    • 11
    • 10
    • 8
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 43
    • 3
    Maus
    Klonalität
    • 44
    • 2
    Monoklonal
    Konjugat
    • 24
    • 6
    • 6
    • 4
    • 3
    • 3
    Dieser PDE8A Antikörper ist unkonjugiert
    Applikation
    • 30
    • 28
    • 27
    • 8
    • 8
    • 7
    • 6
    • 4
    • 1
    Western Blotting (WB)
    Spezifität
    The mouse monoclonal antibody EM-52 recognizes PDE8a (phosphodiesterase 8 A), an approximately 93 kDa intracellular enzyme that hydrolyzes cAMP to 5'AMP.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    Human PDE8a
    Klon
    EM-52
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product PDE8A Primärantikörper
  • Applikationshinweise
    Western blotting: Recommended dilution: 1-2 μg/mL.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Handhabung
    Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    PDE8A (phosphodiesterase 8A (PDE8A))
    Andere Bezeichnung
    PDE8a (PDE8A Produkte)
    Synonyme
    PDE8A antikoerper, Pde8a antikoerper, HsT19550 antikoerper, AI551852 antikoerper, Pde8 antikoerper, RNPDE8A antikoerper, phosphodiesterase 8A antikoerper, PDE8A antikoerper, Pde8a antikoerper, pde8a antikoerper
    Hintergrund
    Phosphodiesterase 8A,PDE8a (high affinity cAMP-specific and IBMX-insensitive 3´,5´-cyclic phosphodiesterase 8 A) is a cyclic nucleotide phosphodiesterase, which hydrolyzes cAMP, an important regulator and mediator of multiple cellular responses to extracellular signals. It is expressed in a wide variety of tissues including testis, ovary, small intestine, and colon. It is not expressed e.g. in thymus. PDE8a is composed of C-terminal catalytic domain containing two putative divalent metal sites and an N-terminal regulatory domain.,HsT19550
    Gen-ID
    5151
    UniProt
    O60658
    Pathways
    cAMP Metabolic Process
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