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PDE8A Antikörper

PDE8A Reaktivität: Human WB Wirt: Maus Monoclonal EM-52 unconjugated
Produktnummer ABIN1690735
  • Target Alle PDE8A Antikörper anzeigen
    PDE8A (phosphodiesterase 8A (PDE8A))
    Reaktivität
    • 41
    • 11
    • 10
    • 8
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 38
    • 3
    Maus
    Klonalität
    • 39
    • 2
    Monoklonal
    Konjugat
    • 24
    • 5
    • 5
    • 3
    • 2
    • 2
    Dieser PDE8A Antikörper ist unkonjugiert
    Applikation
    • 27
    • 25
    • 23
    • 8
    • 8
    • 7
    • 6
    • 4
    • 1
    Western Blotting (WB)
    Spezifität
    The mouse monoclonal antibody EM-52 recognizes PDE8a (phosphodiesterase 8 A), an approximately 93 kDa intracellular enzyme that hydrolyzes cAMP to 5'AMP.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    Human PDE8a
    Klon
    EM-52
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product PDE8A Primärantikörper
  • Applikationshinweise
    Western blotting: Recommended dilution: 1-2 μg/mL.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Handhabung
    Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    PDE8A (phosphodiesterase 8A (PDE8A))
    Andere Bezeichnung
    PDE8a (PDE8A Produkte)
    Hintergrund
    Phosphodiesterase 8A,PDE8a (high affinity cAMP-specific and IBMX-insensitive 3´,5´-cyclic phosphodiesterase 8 A) is a cyclic nucleotide phosphodiesterase, which hydrolyzes cAMP, an important regulator and mediator of multiple cellular responses to extracellular signals. It is expressed in a wide variety of tissues including testis, ovary, small intestine, and colon. It is not expressed e.g. in thymus. PDE8a is composed of C-terminal catalytic domain containing two putative divalent metal sites and an N-terminal regulatory domain.,HsT19550
    Gen-ID
    5151
    UniProt
    O60658
    Pathways
    cAMP Metabolic Process
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