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FIP1L1 Antikörper (AA 501-594) (AbBy Fluor® 350)

FIP1L1 Reaktivität: Human WB, IF (p), IF (cc) Wirt: Kaninchen Polyclonal AbBy Fluor® 350
Produktnummer ABIN1693391
  • Target Alle FIP1L1 Antikörper anzeigen
    FIP1L1 (FIP1 Like 1 (FIP1L1))
    Bindungsspezifität
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 501-594
    Reaktivität
    • 26
    • 7
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 24
    • 2
    Kaninchen
    Klonalität
    • 24
    • 2
    Polyklonal
    Konjugat
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FIP1L1 Antikörper ist konjugiert mit AbBy Fluor® 350
    Applikation
    • 26
    • 12
    • 12
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human FIP1L1
    Isotyp
    IgG
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    Discover our top product FIP1L1 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    FIP1L1 (FIP1 Like 1 (FIP1L1))
    Andere Bezeichnung
    FIP1L1 (FIP1L1 Produkte)
    Synonyme
    FIP1 antikoerper, Rhe antikoerper, hFip1 antikoerper, 1300019H17Rik antikoerper, Rje antikoerper, fip1l1 antikoerper, wu:fd36f11 antikoerper, zgc:103421 antikoerper, factor interacting with PAPOLA and CPSF1 antikoerper, factor interacting with PAPOLA and CPSF1 S homeolog antikoerper, FIP1 like 1 (S. cerevisiae) antikoerper, FIP1 like 1b (S. cerevisiae) antikoerper, fip1l1 antikoerper, FIP1L1 antikoerper, fip1l1.S antikoerper, Fip1l1 antikoerper, fip1l1b antikoerper
    Hintergrund

    Synonyms: DKFZp586K0717, Factor interacting with PAP, FIP1, FIP1 like 1 S cerevisiae, FIP1 like 1, FLJ33619, hFip 1, hFip1, Pre mRNA 3 end processing factor FIP1, Rearranged in hypereosinophilia, RHE, FIP1_HUMAN.

    Background: The Component of the Cleavage and Polyadenylation Specificity Factor (CPSF) complex plays an important role in the 3'-end formation of pre-mRNA. This complex recognizes the AAUAAA signal sequence and interacts with poly(A) polymerase to process and add to the poly(A) tail. FIP1L1 (FIP1-like 1), also known as Pre-mRNA 3'-end-processing factor FIP1, FIP1 (Factor interacting with PAP) and RHE (Rearranged in hypereosinophilia), is a 594 amino acid nuclear protein that is a component of the CPSF complex. Within the complex, FIP1L1 contributes to the poly(A) recognition and stimulates poly(A) addition. Fusion of the genes encoding FIP1L1 and PDGFRA due to an interstitial deletion on chromosome 4q12 is the cause of hypereosinophilia syndrome, a rare blood disorder characterized by continuous overproduction of eosinophils in the bone marrow that leads to tissue infiltration and organ damage. There are three isoforms of FIP1L1 that are produced as a result of alternative splicing events.

    Gen-ID
    81608
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