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EYA3 Antikörper (AA 371-470) (AbBy Fluor® 350)

EYA3 Reaktivität: Human WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 350
Produktnummer ABIN1693978
  • Target Alle EYA3 Antikörper anzeigen
    EYA3 (Eyes Absent Homolog 3 (EYA3))
    Bindungsspezifität
    • 14
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 371-470
    Reaktivität
    • 31
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    Human
    Wirt
    • 31
    Kaninchen
    Klonalität
    • 31
    Polyklonal
    Konjugat
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EYA3 Antikörper ist konjugiert mit AbBy Fluor® 350
    Applikation
    • 28
    • 12
    • 12
    • 10
    • 7
    • 5
    • 5
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human EYA3
    Isotyp
    IgG
    Top Product
    Discover our top product EYA3 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    EYA3 (Eyes Absent Homolog 3 (EYA3))
    Andere Bezeichnung
    EYA3 (EYA3 Produkte)
    Synonyme
    zgc:152966 antikoerper, si:ch211-195b13.2 antikoerper, Xeya3 antikoerper, MGC85199 antikoerper, EYA3 antikoerper, AI844637 antikoerper, EYA transcriptional coactivator and phosphatase 3 antikoerper, EYA transcriptional coactivator and phosphatase 3 L homeolog antikoerper, eya3 antikoerper, eya3.L antikoerper, EYA3 antikoerper, Eya3 antikoerper
    Hintergrund

    Synonyms: AI844637, DKFZp686C132, EYA3, EYA3_HUMAN, Eyes absent 3, Eyes absent 3 homolog Drosophila, Eyes absent homolog 3, OTTMUSP00000010370, RP11-460I13.4, RP23-442A20.1.

    Background: EYA3 is a 573 amino acid protein that localizes to both the nucleus and the cytoplasm and is one of several mammalian homologs of the Drosophila Eya (eyes absent) protein. Existing as two alternatively spliced isoforms, EYA3 possesses magnesium-catalyzed phosphatase activity and is thought to play a role in transcriptional regulation during organogenesis. Specifically, EYA3 interacts with proteins such as Six1 and, via this interaction, functions to activate the expression of genes that are involved in cellular proliferation and organ development. Upon DNA damage, EYA3 may be phosphorylated by ATM or ATR. The gene encoding EYA3 maps to chromosome 1, which spans about 260 million base pairs and comprises nearly 8 % of the human genome.

    Gen-ID
    2140
    Pathways
    Positive Regulation of Response to DNA Damage Stimulus
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