GGA1 Antikörper (AA 51-150) (AbBy Fluor® 350)
-
- Target Alle GGA1 Antikörper anzeigen
- GGA1 (Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 1 (GGA1))
-
Bindungsspezifität
- AA 51-150
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser GGA1 Antikörper ist konjugiert mit AbBy Fluor® 350
-
Applikation
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human GGA1
- Isotyp
- IgG
- Top Product
- Discover our top product GGA1 Primärantikörper
-
-
- Applikationshinweise
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- GGA1 (Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 1 (GGA1))
- Andere Bezeichnung
- GGA1 (GGA1 Produkte)
- Synonyme
- 4930406E12Rik antikoerper, AU016030 antikoerper, AW209092 antikoerper, fb33h10 antikoerper, im:6912200 antikoerper, wu:fb33h10 antikoerper, zgc:101044 antikoerper, putative golgi associated, gamma adaptin ear containing,arf binding protein 1 (gga1) antikoerper, golgi associated, gamma adaptin ear containing, ARF binding protein 1 antikoerper, golgi-associated, gamma adaptin ear containing, ARF binding protein 1 antikoerper, Smp_164030 antikoerper, Gga1 antikoerper, gga1 antikoerper, GGA1 antikoerper
- Hintergrund
-
Synonyms: 4930406E12Rik, ADP ribosylation factor binding protein 1, ADP ribosylation factor binding protein GGA1, ADP-ribosylation factor-binding protein GGA1, ARF binding protein 1, ARF-binding protein 1, Gamma adaptin related protein 1, gamma ear-containing, Gamma-adaptin-related protein 1, GGA 1, GGA1, GGA1 protein, GGA1_HUMAN, Golgi associated gamma adaptin ear containing ARF, Golgi associated gamma adaptin ear containing ARF binding protein 1, Golgi localized gamma ear containing ARF binding protein 1, Golgi-localized, OTTHUMP00000028975, OTTHUMP00000042200.
Background: The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45 % sequence identity with GGA2 and GGA3 (1).
- Gen-ID
- 26088
-