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C4B Antikörper (AA 1454-1550) (AbBy Fluor® 488)

C4b Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 488
Produktnummer ABIN1694516
  • Target Alle C4B (C4b) Antikörper anzeigen
    C4B (C4b) (Complement Component C4b (C4b))
    Bindungsspezifität
    • 14
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1454-1550
    Reaktivität
    • 43
    • 21
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 55
    • 4
    • 3
    Kaninchen
    Klonalität
    • 58
    • 4
    Polyklonal
    Konjugat
    • 19
    • 8
    • 8
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser C4B Antikörper ist konjugiert mit AbBy Fluor® 488
    Applikation
    • 30
    • 23
    • 14
    • 12
    • 12
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Complement C4 gamma chain
    Isotyp
    IgG
    Top Product
    Discover our top product C4b Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    C4B (C4b) (Complement Component C4b (C4b))
    Andere Bezeichnung
    Complement C4 gamma chain (C4b Produkte)
    Synonyme
    C4B1 antikoerper, C4B12 antikoerper, C4B2 antikoerper, C4B3 antikoerper, C4B5 antikoerper, C4BD antikoerper, C4B_2 antikoerper, C4F antikoerper, CH antikoerper, CO4 antikoerper, CPAMD3 antikoerper, C4 antikoerper, C4A2 antikoerper, C4A3 antikoerper, C4A4 antikoerper, C4A6 antikoerper, C4AD antikoerper, C4S antikoerper, CPAMD2 antikoerper, RG antikoerper, wu:fi14a03 antikoerper, C4B antikoerper, DKFZP469I0332 antikoerper, Slp antikoerper, Ss antikoerper, C4-2 antikoerper, C4l antikoerper, complement C4B (Chido blood group) antikoerper, complement C4A (Rodgers blood group) antikoerper, complement component 4 antikoerper, complement C4-B antikoerper, complement component 4B (Chido blood group) antikoerper, complement component 4A (Rodgers blood group) antikoerper, C4B antikoerper, C4A antikoerper, c4 antikoerper, LOC462577 antikoerper, C4a antikoerper, C4b antikoerper
    Hintergrund

    Synonyms: C4, RG, C4S, CO4, C4A2, C4A3, C4A4, C4A6, C4AD, CPAMD2, CH, C4F, C4B1, C4B2, C4B3, C4B5, C4BD, C4B12, C4B_2, CPAMD3, Complement C4-A, Acidic complement C4, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2, C4A

    Background: Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens. Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

    Gen-ID
    720721
    UniProt
    P0C0L4
    Pathways
    Komplementsystem
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