GnRH2 Antikörper (AA 1-80) (AbBy Fluor® 488)

Produktnummer ABIN1694559

Produktdetails anti-GnRH2 Antikörper (AbBy Fluor® 488)

Target: GnRH2 (Gonadotropin-Releasing Hormone 2 (GnRH2))

Bindungsspezifität: AA 1-80

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GnRH2 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GNRH2/GnRH II

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GnRH2

Target: GnRH2 (Gonadotropin-Releasing Hormone 2 (GnRH2))

Andere Bezeichnung: GNRH2 (GnRH2 Produkte)

Synonyme: GnRH-II antikoerper, cGnRH-II antikoerper, GnRHII antikoerper, LH-RHII antikoerper, Gn-RHII antikoerper, gnrh2 antikoerper, cgnrh-ii antikoerper, gonadotropin-releasing hormone 2 antikoerper, gonadotropin releasing hormone 2 antikoerper, chicken II type gonadotropin-releasing hormone precursor antikoerper, gnrh2 antikoerper, GNRH2 antikoerper, LOC100135862 antikoerper

Hintergrund:

Synonyms: GnRH II, GnRH-associated peptide 2, GnRH-associated peptide II, gnrh2, GON2_HUMAN, Gonadoliberin II, Gonadotropin-releasing hormone 2, Gonadotropin-releasing hormone II, LH-RH II, Luliberin II, Luteinizing hormone-releasing hormone II, Progonadoliberin 2, Progonadoliberin II.

Background: Human reproduction is controlled by the hypothalaic-pituitary gonadal axis laid down early in fetal development. Gonadotropin releasing hormone (GnRH), also known as GnRH-associated peptide, luteinizing hormone releasing hormone (LHRH), luliberin or gonadorelin, is a decapeptide that is an important molecule in the hypothalamic-pituitary-gonadal axis control circuit. GnRH is produced by hypothalamic neurons and secreted in a pulsatile manner into the capillary plexus of the medianeminence. GnRH affects the release of lutenizing hormone and follicle stimulating hormone from gonadotropic cells in the anterior pituitary. In addition to hypothalamic GnRH (GnRH I), a second GnRH form (GnRH II) functions primarily in the midbrain. GnRH is expressed in the acrosomal region of human sperm and in the anterior pituitary tissue and cancer cells. Unlike GnRH I, GnRH II is highly expressed outside the brain, particularly in the kidney, bone marrow and prostate, suggesting that it may have multiple functions. GnRH binds to a specific G protein-coupled receptor in the pituitary to regulate synthesis and secretion of gonadotropins.

Gen-ID: 2797

Pathways: Hormone Activity