DOK7 Antikörper (AA 21-120) (AbBy Fluor® 488)
-
- Target Alle DOK7 Antikörper anzeigen
- DOK7 (Docking Protein 7 (DOK7))
-
Bindungsspezifität
- AA 21-120
-
Reaktivität
- Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser DOK7 Antikörper ist konjugiert mit AbBy Fluor® 488
-
Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Ratte
- Homologie
- Human,Mouse,Dog,Cow,Sheep,Pig,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human DOK7
- Isotyp
- IgG
- Top Product
- Discover our top product DOK7 Primärantikörper
-
-
- Applikationshinweise
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- DOK7 (Docking Protein 7 (DOK7))
- Andere Bezeichnung
- DOK7 (DOK7 Produkte)
- Synonyme
- si:dkey-180b4.3 antikoerper, si:ch211-164d19.2 antikoerper, C4orf25 antikoerper, CMS1B antikoerper, A930013K19Rik antikoerper, AW049091 antikoerper, Dok-7 antikoerper, EF-12 antikoerper, Oit5 antikoerper, RGD1566416 antikoerper, dok-7 antikoerper, docking protein 7 antikoerper, DOK7 antikoerper, dok7 antikoerper, Dok7 antikoerper
- Hintergrund
-
Synonyms: Docking protein 7, DOK 7, DOK7, DOK7_HUMAN, Downstream of tyrosine kinase 7, Protein Dok-7.
Background: The downstream of kinase family (Dok1-7) are members of a class of docking? proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Based on their similarities, the Dok family of proteins can be divided into three subgroups: Dok-1/2/3, Dok-4/5/6 and Dok-7. Through its interaction with muscle-specific receptor kinase (MuSK), Dok-7 is crucial for neuromuscular synaptogenesis and for MuSK activation. Mice lacking Dok-7 do not form neuromuscular synapses nor acetylcholine receptor clusters. Mutations in the Dok-7 gene can cause congenital myasthenic syndromes (CMA) recessively inherited disorders characterized by muscle weakness.
- Pathways
- Skeletal Muscle Fiber Development
-