SPAG9 Antikörper (AA 101-188) (AbBy Fluor® 488)

Produktnummer ABIN1695078

Produktdetails anti-SPAG9 Antikörper (AbBy Fluor® 488)

Target: SPAG9 (Sperm Associated Antigen 9 (SPAG9))

Bindungsspezifität: AA 101-188

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPAG9 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Sheep,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human JLP/JIP-4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SPAG9

Target: SPAG9 (Sperm Associated Antigen 9 (SPAG9))

Andere Bezeichnung: JLP/JIP-4 (SPAG9 Produkte)

Synonyme: CT89 antikoerper, HLC-6 antikoerper, HLC4 antikoerper, JIP-4 antikoerper, JIP4 antikoerper, JLP antikoerper, PHET antikoerper, PIG6 antikoerper, 3110018C07Rik antikoerper, 4733401I23Rik antikoerper, 4831406C20Rik antikoerper, AW552012 antikoerper, JSAP2 antikoerper, JSAP2a antikoerper, Jip4 antikoerper, Mapk8ip4 antikoerper, syd1 antikoerper, sperm associated antigen 9 antikoerper, JNK-associated leucine-zipper protein antikoerper, C-Jun-amino-terminal kinase-interacting protein 4 antikoerper, SPAG9 antikoerper, Spag9 antikoerper, Bm1_41390 antikoerper, LOC100186844 antikoerper

Hintergrund:

Synonyms: C jun amino terminal kinase interacting protein 4, c Jun NH2 terminal kinase associated leucine zipper protein, FLJ13450, FLJ14006, FLJ34602, HLC 4, HLC 4 protein, HLC 6, HLC4, HLC4 protein, HLC6, HSS, Human lung cancer protein 6, Human lung cancer protein 6, JIP 4, JIP 4, JIP4, JNK associated leucine zipper protein 1, JNK associated leucine zipper protein, JNK interacting protein 4, JNK interacting protein 4, JNK interacting protein, JNK/SAPK associated protein, KIAA0516, Lung cancer oncogene 4, MAPK8IP4, Max binding protein, MGC117291, MGC14967, MGC74461, Mitogen activated protein kinase 8 interacting protein 4, Mitogen activated protein kinase 8 interacting protein 4, PHET, PIG 6, PIG6, proliferation inducing gene 6, Protein highly expressed in testis, SPAG 9, SPAG9, Sperm associated antigen 9, Sperm specic protein, Sperm surface protein, Sunday driver drosophila homolog, Sunday driver 1, SYD1, JIP4_HUMAN.

Background: JIP-4 is a 1,321 amino acid protein encoded by the human gene SPAG9. It contains a large N-terminal extracellular domain, a short transmembrane helical domain, and a cytoplasmic domain. There are 6 N-glycosylation sites, several phosphorylation sites for cAMP/cGMP-dependent protein kinase, protein kinase C, and casein kinase II, and 10 putative myristoylation sites. There is also a leucine zipper motif, with 6 leucine repeats, that may aid in dimerization since there is no upstream basic domain characteristic of DNA binding proteins. The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP-4 is a cytoplasmic, perinuclear protein that has eight known isoforms whose expression varies by tissue and disease state.

Gen-ID: 9043

UniProt: O60271

Pathways: Regulation of Muscle Cell Differentiation