DGAT2 Antikörper (AA 251-360) (AbBy Fluor® 488)

Produktnummer ABIN1695191

Produktdetails anti-DGAT2 Antikörper (AbBy Fluor® 488)

Target: DGAT2 (Diacylglycerol O-Acyltransferase 2 (DGAT2))

Bindungsspezifität: AA 251-360

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DGAT2 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DGAT2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu DGAT2

Target: DGAT2 (Diacylglycerol O-Acyltransferase 2 (DGAT2))

Andere Bezeichnung: DGAT2 (DGAT2 Produkte)

Synonyme: ARAT antikoerper, GS1999FULL antikoerper, hmfn1045 antikoerper, 0610010B06Rik antikoerper, DGAT-2 antikoerper, zgc:113394 antikoerper, DDBDRAFT_0188804 antikoerper, DDBDRAFT_0233097 antikoerper, DDB_0188804 antikoerper, DDB_0233097 antikoerper, diacylglycerol O-acyltransferase 2 antikoerper, diacylglycerol O-acyltransferase 2 L homeolog antikoerper, diacylglycerol acyltransferase family antikoerper, DGAT2 antikoerper, dgat2 antikoerper, Dgat2 antikoerper, dgat2.L antikoerper

Hintergrund:

Synonyms: DGAT2, DGAT2_HUMAN, Diacylglycerol O acyltransferase like protein 2, Diacylglycerol O-acyltransferase 2, Diacylglycerol O-acyltransferase homolog 2 mouse, Diacylglycerol O-acyltransferase homolog 2, Diacylglycerol O-acyltransferase-like protein 2 isoform 1, Diglyceride acyltransferase 2, DKFZp686A15125, GS1999full, HMFN1045.

Background: Glucose and insulin are anabolic signals which upregulate the transcriptions of a series of lipogenic enzymes to convert excess carbohydrate into triglycerides for efficient energy storage. Acyl-coenzyme A:diacylglycerol acyltransferase, also known as DGAT1 and ARGP1, is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides. DGAT1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol (DAG) and fatty acyl CoA as substrates. DGAT1 plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism, such as intestinal fat absorption, lipoprotein assembly, adipose tissue form-ation and lactation. DGAT2, which has no homology to DGAT1, differs from DGAT1 in that its activity has been shown to be inhibited by MgCl in an in vitro assay. DGAT2 is expressed primarily in liver and white adipose tissue, which suggests that it plays an important role in mammalian triglyceride metabolism.

Gen-ID: 84649

UniProt: Q96PD7