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Supervillin Antikörper (AA 51-150) (AbBy Fluor® 488)

SVIL Reaktivität: Maus WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 488
Produktnummer ABIN1695284
  • Target Alle Supervillin (SVIL) Antikörper anzeigen
    Supervillin (SVIL)
    Bindungsspezifität
    • 14
    • 5
    • 3
    • 2
    • 1
    • 1
    AA 51-150
    Reaktivität
    • 16
    • 15
    Maus
    Wirt
    • 24
    • 5
    • 1
    Kaninchen
    Klonalität
    • 26
    • 4
    Polyklonal
    Konjugat
    • 10
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Supervillin Antikörper ist konjugiert mit AbBy Fluor® 488
    Applikation
    • 30
    • 12
    • 12
    • 8
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Supervillin
    Isotyp
    IgG
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  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Supervillin (SVIL)
    Andere Bezeichnung
    Supervillin (SVIL Produkte)
    Synonyme
    sb:cb867 antikoerper, svil antikoerper, wu:fd05a09 antikoerper, SVIL antikoerper, DKFZp468F0819 antikoerper, AU024053 antikoerper, B430302E16Rik antikoerper, supervillin a antikoerper, supervillin antikoerper, supervillin, putative antikoerper, svila antikoerper, SVIL antikoerper, LOC5577073 antikoerper, CpipJ_CPIJ003700 antikoerper, Smp_148580 antikoerper, svil antikoerper, Svil antikoerper
    Hintergrund

    Synonyms: Supervillin, Archvillin, p205/p250, SVIL

    Background: Forms a high-affinity link between the actin cytoskeleton and the membrane. Isoform 1 (archvillin) is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation. Appears to be involved in myosin II assembly. May modulate myosin II regulation through MLCK during cell spreading, an initial step in cell migration. May play a role in invadopodial function. Isoform 2 may be involved in modulation of focal adhesions. Supervillin-mediated down-regulation of focal adhesions involves binding to TRIP6. Plays a role in cytokinesis through KIF14 interaction (By similarity).

    Gen-ID
    6840
    UniProt
    O95425
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