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G6PC2 Antikörper (AbBy Fluor® 488)

G6PC2 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal AbBy Fluor® 488
Produktnummer ABIN1695428
  • Target Alle G6PC2 Produkte
    G6PC2 (Glucose-6-Phosphatase, Catalytic, 2 (G6PC2))
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 22
    Kaninchen
    Klonalität
    • 22
    Polyklonal
    Konjugat
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser G6PC2 Antikörper ist konjugiert mit AbBy Fluor® 488
    Applikation
    • 17
    • 7
    • 1
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Human
    Homologie
    Mouse,Rat,Cow,Sheep,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Glucose 6 phosphatase 2/IGRP
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    G6PC2 (Glucose-6-Phosphatase, Catalytic, 2 (G6PC2))
    Andere Bezeichnung
    Glucose 6 Phosphatase 2/Igrp (G6PC2 Produkte)
    Synonyme
    IGRP antikoerper, G6pc-rs antikoerper, Igrp antikoerper, g6pc2 antikoerper, igrp antikoerper, glucose-6-phosphatase catalytic subunit 2 antikoerper, glucose-6-phosphatase, catalytic, 2 antikoerper, glucose-6-phosphatase, catalytic, 2 S homeolog antikoerper, G6PC2 antikoerper, G6pc2 antikoerper, g6pc2.S antikoerper
    Hintergrund

    Synonyms: G 6 Pase 2, G 6 Pase2, G6Pase 2, G6Pase2, G6PC 2, G6pc rs, G6pcrs, Glucose 6 phosphatase 2, Glucose 6 phosphatase, catalytic, 2, Glucose 6 phosphatase, catalytic, related, Glucose 6 phosphate catalytic 2, Islet specic G6CP related protein, Islet specic glucose 6 phosphatase, Islet specic glucose 6 phosphatase catalytic subunit related protein, G6PC2_HUMAN.

    Background: Glucose-6-phosphatase (G6Pase), is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate in the final step of gluconeogenesis and gluconeolysis. G6Pase localizes to the endoplasmic reticulum, and while liver, kidney, and intestine are the only tissues that express the first identified isoform, G6Pase-alpha, a second form, designated G6Pase-, contributes to blood glucose homeostasis in a wider range of tissues. Islet-specific G-6-Pase catalytic subunit-related protein (IGRP), a homolog of the catalytic subunit of G6Pase, may play a role in the regulation of islet metabolism and in insulin secretion induced by metabolites. The exact catalytic acivity of IGRP is not defined. Identification of inhibitors of IGRP have potential therapeutic benefits for treatment of type 2 diabetes resulting from insulin secretion defects. Structurally, IGRP has been shown to be a glycoprotein held in the endoplasmic reticulum by nine transmembrane domains, which are then degraded in cells through the proteasome pathway generating MHC class I presented peptides.

    Gen-ID
    57818
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