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Complement Component C9b (C9b) (AA 251-350) Antikörper (AbBy Fluor® 488)

C9b Reaktivität: Human, Maus WB, FACS Wirt: Kaninchen Polyclonal AbBy Fluor® 488
Produktnummer ABIN1695768
  • Target Alle Complement Component C9b (C9b) Antikörper anzeigen
    Complement Component C9b (C9b)
    Bindungsspezifität
    • 15
    • 15
    AA 251-350
    Reaktivität
    Human, Maus
    Wirt
    • 30
    Kaninchen
    Klonalität
    • 30
    Polyklonal
    Konjugat
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AbBy Fluor® 488
    Applikation
    • 30
    • 13
    • 13
    • 13
    • 6
    • 6
    • 3
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Dog,Cow,Sheep,Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Complement component C9b
    Isotyp
    IgG
    Top Product
    Discover our top product C9b Primärantikörper
  • Applikationshinweise
    FCM 1:20-100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Complement Component C9b (C9b)
    Andere Bezeichnung
    Complement component C9b (C9b Produkte)
    Synonyme
    C9 antikoerper, complement C9 antikoerper, proteasome (prosome, macropain) subunit, alpha type 4 antikoerper, C9 antikoerper, Psma4 antikoerper
    Hintergrund

    Synonyms: CO9_HUMAN, Complement component C9, Complementcomponent C9b.

    Background: C9 is a plasma protein synthesized in the liver and monocytes consisting of a single polypeptide chain. C9 is a part of the membrane attack complex (MAC), an important component of the immune system. The MAC forms upon complement system activation by invading pathogenic bacteria and consists of the four major complement proteins: C5b, C6, C7 and C8. These complement proteins bind to the outer surface of the plasma membrane of the invading cell. C9 binds to the membrane associated C5b-8 protein, which leads to the circular polymerization of 12-18 C9 Molecules. These polymerized C9 Molecules form a ring structure in the membrane. Molecules can then diffuse freely through this transmembrane channel, causing cell lysis and destruction of the invading bacterial cell.

    Gen-ID
    735
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