EYA2 Antikörper (AA 201-300) (AbBy Fluor® 488)
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- Target Alle EYA2 Antikörper anzeigen
- EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))
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Bindungsspezifität
- AA 201-300
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Reaktivität
- Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser EYA2 Antikörper ist konjugiert mit AbBy Fluor® 488
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Ratte
- Homologie
- Human,Mouse,Dog,Cow,Sheep,Pig,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human EYA2
- Isotyp
- IgG
- Top Product
- Discover our top product EYA2 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))
- Andere Bezeichnung
- EYA2 (EYA2 Produkte)
- Synonyme
- EYA2 antikoerper, zgc:92279 antikoerper, eab1 antikoerper, Eab1 antikoerper, EAB1 antikoerper, EYA transcriptional coactivator and phosphatase 2 antikoerper, EYA2 antikoerper, eya2 antikoerper, Eya2 antikoerper
- Hintergrund
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Synonyms: EAB 1, EAB1, EYA 2, EYA2, EYA2_HUMAN, eyes absent 2 homolog Drosophila, Eyes absent homolog 2, Translation of this uORF probably lowers the translation efficiency of EYA2.
Background: A gene on chromosome 20q13.1 encodes Eya2 (eyes absent). EYA2 is one of four members of the eyes absent family. A 271 amino acid domain at the carboxy-terminal is highly conserved amongst the members of the eyes absent family, while the PST (proline-serive-threonin)-rich amino-terminal is highly divergent. EYA2 is expressed relatively late in development in the cytoplasm of extensor tendons and ligaments of the phalangeal elements of the limb, cranial placodes, branchial arches, central nervous system, and the developing eye. Pax3 induces the expression of Eya2 in a cascade that is necessary and sufficient for myogenesis. EYA2, like EYA1, acts as a transcriptional activator in connective tissue patterning through its PST domain, which functions as a transactivation domain. EYA2 is translocated to the nucleus by Six proteins, which interact through their domain and homeodomain with EYA2. EYA2 carboxy-terminal interacts with the G Alpha z and G Alphai 2 proteins. This interaction prevents Six proteins from translocating EYA2 to the nucleus.
- Gen-ID
- 2139
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