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PRICKLE1 Antikörper (AA 551-650) (AbBy Fluor® 488)

PRICKLE1 Reaktivität: Ratte IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 488
Produktnummer ABIN1695921
  • Target Alle PRICKLE1 Antikörper anzeigen
    PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))
    Bindungsspezifität
    • 14
    • 8
    • 8
    • 2
    AA 551-650
    Reaktivität
    • 19
    • 16
    • 3
    Ratte
    Wirt
    • 31
    • 2
    Kaninchen
    Klonalität
    • 32
    • 1
    Polyklonal
    Konjugat
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PRICKLE1 Antikörper ist konjugiert mit AbBy Fluor® 488
    Applikation
    • 19
    • 19
    • 12
    • 12
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Ratte
    Homologie
    Human,Mouse,Dog,Cow,Sheep,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Prickle
    Isotyp
    IgG
    Top Product
    Discover our top product PRICKLE1 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))
    Andere Bezeichnung
    Prickle (PRICKLE1 Produkte)
    Synonyme
    EPM1B antikoerper, RILP antikoerper, Rilp antikoerper, 1110058P22Rik antikoerper, AW215793 antikoerper, Prickle antikoerper, mpk1 antikoerper, XPk antikoerper, pk-B antikoerper, prickle antikoerper, prickle-B antikoerper, Prickle-b antikoerper, prickle planar cell polarity protein 1 antikoerper, prickle planar cell polarity protein 1 L homeolog antikoerper, prickle planar cell polarity protein 1 S homeolog antikoerper, PRICKLE1 antikoerper, Prickle1 antikoerper, prickle1.L antikoerper, prickle1.S antikoerper
    Hintergrund

    Synonyms: FLJ31627, FLJ31937, MGC138902, MGC138903, EPM1B, Prickle 1, Prickle homolog 1 Drosophila, Prickle like protein 1, Prickle-like 1, Prickle1, REST-Interacting LIM Domain Protein, REST/NRSF interacting LIM domain protein 1, RILP, PRIC1_HUMAN.

    Background: Prickle1 is an 831 amino acid protein that contains one PET domain and three LIM zinc-binding domains and localizes to the cytoplasm, as well as to the nuclear membrane. Expressed at higher levels in placenta and at lower levels in liver, brain, kidney, lung and pancreas, Prickle1 is thought to function as a nuclear receptor that interacts with NRSF, a silencer protein that binds the DNA sequence element NRSE (neuron-restrictive silencer element). Defects in the gene encoding Prickle1 are associated with autosomal recessive progressive myoclonic epilepsy-1B, which is characterized by quick jerks of the arms, shoulders or legs. The gene encoding Prickle1 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5 % of the human genome.

    Gen-ID
    144165
    Pathways
    WNT Signalweg, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development, Protein targeting to Nucleus
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