ANO3 Antikörper (AA 801-900) (AbBy Fluor® 488)

Produktnummer ABIN1695944

Produktdetails anti-ANO3 Antikörper (AbBy Fluor® 488)

Target: ANO3 (Anoctamin 3 (ANO3))

Bindungsspezifität: AA 801-900

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANO3 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TMEM16C/Anoctamin 3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ANO3

Target: ANO3 (Anoctamin 3 (ANO3))

Andere Bezeichnung: TMEM16C/Anoctamin 3 (ANO3 Produkte)

Synonyme: TMEM16C antikoerper, anoctamin-3 antikoerper, C11orf25 antikoerper, DYT23 antikoerper, DYT24 antikoerper, AI838058 antikoerper, B230324K02Rik antikoerper, Tmem16c antikoerper, anoctamin 3 antikoerper, anoctamin-3 antikoerper, ANO3 antikoerper, LOC100453980 antikoerper, ano3 antikoerper, Ano3 antikoerper

Hintergrund:

Synonyms: ANO3, C11orf25, GENX 3947, TMEM16C, Transmembrane protein 16C eight membrane spanning domains, Transmembrane protein 16C, ANO3_HUMAN.

Background: TMEM16C is a 981 amino acid multi-pass membrane protein that is encoded by a gene which maps to chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4 % of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

Gen-ID: 63982