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DAZ4 Antikörper (AA 51-150) (AbBy Fluor® 488)

DAZ4 Reaktivität: Maus WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 488
Produktnummer ABIN1696052
  • Target Alle DAZ4 Antikörper anzeigen
    DAZ4 (Deleted In Azoospermia 4 (DAZ4))
    Bindungsspezifität
    • 14
    • 7
    • 7
    • 6
    • 6
    • 3
    • 1
    • 1
    AA 51-150
    Reaktivität
    • 29
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 42
    • 1
    Kaninchen
    Klonalität
    • 43
    Polyklonal
    Konjugat
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DAZ4 Antikörper ist konjugiert mit AbBy Fluor® 488
    Applikation
    • 35
    • 18
    • 17
    • 12
    • 12
    • 6
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Dog,Cow,Sheep,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human DAZ4
    Isotyp
    IgG
    Top Product
    Discover our top product DAZ4 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    DAZ4 (Deleted In Azoospermia 4 (DAZ4))
    Andere Bezeichnung
    DAZ4 (DAZ4 Produkte)
    Synonyme
    pDP1680 antikoerper, pDP1681 antikoerper, DAZ4 antikoerper, deleted in azoospermia 4 antikoerper, DAZ4 antikoerper
    Hintergrund

    Synonyms: DAZ4, Deleted in azoospermia 4, Deleted in azoospermia protein 4.

    Background: Spermatogenesis is the process by which male spermatogonia develop into mature spermatozoa. DAZ (deleted in azoospermia) are RNA-binding proteins that play an essential role in spermatogenesis. DAZ proteins influence the first stages of spermatogenesis and the maintenance of germ cell populations. DAZ proteins (DAZ1, DAZ2, DAZ3, DAZ4 and DAZ5) are encoded by separate genes on chromosome Y, each of which contain an AZFc domain in their coding region. DAZ proteins localize to the nucleus of spermatogonia, but relocate to the cytoplasm during meiosis. DAZ proteins contain an RRM (RNA recognition motif) domain that may regulate mRNA translation by binding to the 3?UTR. Deletions in the genes encoding DAZ proteins may cause azoospermia or oligospermia which can lead to male infertility. DAZ4 (deleted in azoospermia 4), also known as pDP1680 or pDP1681, is a 579 amino acid testis specific protein that contains nine DAZ-like domains and two RNA recognition motifs (RRM). DAZ4 exists as two alternatively spliced isoforms.

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