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SYPL1 Antikörper (AA 121-220) (AbBy Fluor® 488)

SYPL1 Reaktivität: Maus WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 488
Produktnummer ABIN1696104
  • Target Alle SYPL1 Produkte
    SYPL1 (Synaptophysin-Like 1 (SYPL1))
    Bindungsspezifität
    • 14
    • 10
    • 8
    • 6
    • 2
    AA 121-220
    Reaktivität
    • 19
    • 18
    • 4
    • 2
    • 2
    • 2
    • 1
    Maus
    Wirt
    • 34
    Kaninchen
    Klonalität
    • 34
    Polyklonal
    Konjugat
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SYPL1 Antikörper ist konjugiert mit AbBy Fluor® 488
    Applikation
    • 34
    • 16
    • 14
    • 12
    • 12
    • 6
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Cow,Pig,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Pantophysin
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    SYPL1 (Synaptophysin-Like 1 (SYPL1))
    Andere Bezeichnung
    Pantophysin (SYPL1 Produkte)
    Synonyme
    Sypl antikoerper, H-SP1 antikoerper, SYPL antikoerper, AI314763 antikoerper, AI604763 antikoerper, D12Ertd446e antikoerper, PanI antikoerper, Pphn antikoerper, Sypl1 antikoerper, synaptophysin like 1 antikoerper, synaptophysin-like 1 antikoerper, synaptophysin-like protein antikoerper, SYPL1 antikoerper, Sypl1 antikoerper, Sypl antikoerper
    Hintergrund

    Synonyms: SYPL1_HUMAN, Synaptophysin-like protein 1, Pantophysin, SYPL1, H-SP1, SYPL.

    Background: The MARVEL domain is a 130 amino acid motif that contains four transmembrane helices, both of which have cytoplasmic N- and C-terminal regions. MARVEL domain-containing proteins are thought to participate in tight junction regulation, the biogenesis of vesicular transport carriers and in cholesterol-rich membrane apposition events. Pantophysin, also known as SYPL1 (synaptophysin-like protein 1) or H-SP1, is a 259 amino acid multi-pass membrane protein that localizes to melanosomes and vesicles, as well as to the cytoplasm, and contains one MARVEL domain. Expressed as multiple alternatively spliced isoforms, pantophysin is present in tissues throughout the body where it may play a role in vesicle trafficking and protein transport. The gene encoding pantophysin maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5 % of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

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