ODF2 Antikörper (AA 1-100) (AbBy Fluor® 555)
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- Target Alle ODF2 Antikörper anzeigen
- ODF2 (Outer Dense Fiber of Sperm Tails 2 (ODF2))
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Bindungsspezifität
- AA 1-100
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Reaktivität
- Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ODF2 Antikörper ist konjugiert mit AbBy Fluor® 555
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Ratte
- Homologie
- Human
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ODF2/Cenexin1
- Isotyp
- IgG
- Top Product
- Discover our top product ODF2 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- ODF2 (Outer Dense Fiber of Sperm Tails 2 (ODF2))
- Andere Bezeichnung
- ODF2/Cenexin1 (ODF2 Produkte)
- Synonyme
- odf84 antikoerper, odf2/1 antikoerper, odf2/2 antikoerper, DKFZp469J0214 antikoerper, CT134 antikoerper, ODF2/1 antikoerper, ODF2/2 antikoerper, ODF84 antikoerper, si:dkey-228b2.4 antikoerper, AI848335 antikoerper, MMTEST29 antikoerper, outer dense fiber of sperm tails 2 antikoerper, outer dense fiber of sperm tails 2a antikoerper, outer dense fiber of sperm tails 2 L homeolog antikoerper, ODF2 antikoerper, odf2 antikoerper, odf2a antikoerper, odf2.L antikoerper, Odf2 antikoerper
- Hintergrund
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Synonyms: sperm tail structural protein, 84 kDa outer dense fiber protein, Cenexin 1, Cenexin1 variant 1, KKT 4, KKT4, ODF 2, ODF 84, ODF2, ODF2/1, ODF2/2, ODF84, Outer dense fiber of sperm tail 2, Outer dense fiber of sperm tails 2, outer dense fiber of sperm tails, Outer dense fiber of sperm tails protein 2, Outer dense fiber of sperm tails, 84 kD, Outer dense fiber protein 2, Sperm outer dense fiber major protein 2, Testis specic autoantigen, ODFP2_HUMAN.
Background: Cenexin1 is an isoform of ODF2, that unlike ODF2 is present in several somatic cell types. Cenexin1 acts as a general scaffold protein that is specifically localised to the distal/subdistal appendages of mother centrioles. Cenexin1 is required for proper localization of Plk1 to the centrosomes. This centrosomal localization of Plk1 is required for proper microtubule function. Cenexin1 recruits Plk1 via a C-terminal extension of cenexin1 that is not present in ODF2. Cenexin1 is required for proper mitotic progression, depletion of Cenexin1 µLtimately leads to chromosome missegregation and apoptosis. The ODF2 (outer dense fiber 2) gene encodes both ODF2 and Cenexin1, which have very different functions. ODF2 is a major component of sperm tail outer dense fibers (ODFs). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. They may help to maintain the passive elastic structures and elastic recoil of the sperm tail, and may also modulate sperm motility.
- Gen-ID
- 4957
- Pathways
- M Phase
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